PSAQ Methode

Absolute protein quantification
  

 

Since 2010, PX'Therapeutics offers absolute protein quantification based on mass spectrometry analysis, through its subsidiary PROMISE Advanced Proteomics.

This innovative method uses brand-new quantification standards (full-length stable-isotope-labelled proteins) and provides highly specific and accurate results for proteins present in biological fluids even at very low concentrations.

 

 

Applications:

 

 Therapeutic proteins:

 Bioanalysis

 Pharmacokinetic studies

 Clinical: diagnostic/theranostic

 Biomarker evaluation/validation

 Companion diagnostics

 Quality controls:

 Food quality control (dosage of enterotoxins, etc.)

 Doping control (dosage of drugs/metabolites)

 

 

Advantages:


• Accurate and sensitive quantification at ng/mL concentrations in complex matrices

 Fast method development (≠ ELISA)
• 
Without using antibody

 Discrimination of protein isoforms

 Multiplex quantification: up to 50 in a single analysis


 

Our services:


• Engineering and manufacturing of stable-isotope-labelled therapeutic proteins to be used as quantification standards 
Development of quantitative mass spectrometry assays (SRM analysis) and sample analysis 



More info at www.promise-proteomics.com